Shallow genomics, phylogenetics, and evolution in the family Drosophilidae

Zilversmit M, O'Grady P, Desalle R

American Museum of Natural History, Department of Invertebrate Zoology, Central Park West @ 79th Street, New York, NY 10024, USA.

Pac Symp Biocomput. 2002;:512-23.


The effects of the genomic revolution are beginning to be felt in all disciplines of the biological sciences. Evolutionary biology in general, and phylogenetic systematics in particular, are being revolutionized by these advances. The advent of rapid nucleotide sequencing techniques have provided phylogenetic biologists with the tools required to quickly and efficiently generate large amounts of character information. We use family Drosophilidae as a model system to study phylogenetics and genome evolution by combining high throughput sequencing methods from the field genomics and standard phylogenetic methodology. This paper presents preliminary results from this work. Separate data partitions, based on either gene function or linkage group, are compared to a combined analysis of all the data to assess support on phylogenetic trees.

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