A methodology to migrate the gene ontology to a description logic environment using DAML+OIL

Wroe CJ, Stevens R, Goble CA, Ashburner M

Department of Computer Science, University of Manchester, Oxford Rd, Manchester, M13 9PL, UK. cwroe@cs.man.ac.uk

Pac Symp Biocomput. 2003;:624-35.


Abstract

The Gene Ontology Next Generation Project (GONG) is developing a staged methodology to evolve the current representation of the Gene Ontology into DAML+OIL in order to take advantage of the richer formal expressiveness and the reasoning capabilities of the underlying description logic. Each stage provides a step level increase in formal explicit semantic content with a view to supporting validation, extension and multiple classification of the Gene Ontology. The paper introduces DAML+OIL and demonstrates the activity within each stage of the methodology and the functionality gained.


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