Modeling and Simulation with Hybrid Functional Petri Nets of the Role of Interleukin-6 in Human Early HaematopoiesisTroncale S, Tahi F, Campard D, Vannier JP, Guespin J
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AbstractThe regulation of human haematopoiesis is a complex biological system with numerous
interdependent processes. In vivo Haematopoietic Stem Cells (HSCs) selfrenew
so as to maintain a constant pool of these cells. It would be very interesting
to maintain these cells in vitro, in view of their therapeutical importance. Unfortunately,
there is currently no known process to activate HSCs self-renewal in
vitro.
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