TUMOR HAPLOTYPE ASSEMBLY ALGORITHMS FOR CANCER GENOMICS


DEREK AGUIAR1, WENDY S.W. WONG2, SORIN ISTRAIL3



1Department of Computer Science and Center for Computational Molecular Biology, Brown University, 2Inova Translational Medicine Institute, Inova Health Systems
Email: Sorin_ Istrail@ brown. edu1, wendy. wong@ inova. org2

Pacific Symposium on Biocomputing 19:3-14(2014)


Abstract

To describe the HapCompass-Tumor a computational modeling and algorithmic framework for haplotype assembly of copy number variable cancer genomes containing haplotypes at different frequencies and complex variation.


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