Overcoming health disparities in precision medicine
A session of the Pacific Symposium of Bioinformatics
Big Island of Hawaii, January 3-7, 2024
Precision medicine and public health depend on identifying disease determinants and understanding their biology to develop risk reduction and treatment improvement strategies. However, racial and ethnic disparities exist across patient, provider, and health system levels due to a combination of social, psychosocial, lifestyle, environmental, and biological factors. As minority populations in the US grow and precision medicine expands globally, it is crucial to invest in efforts to characterize, understand, and eliminate these disparities. The 2024 Pacific Symposium on Biocomputing aims to build upon the successful 2023 session by highlighting new analyses, methods, algorithms, and datasets that can be applied throughout the research-to-translation continuum to address disparities in precision medicine.
Topics within the scope of this session include:
Genomic research and its translation
Methods for trans-ancestry GWAS
Leveraging genetic variation across world populations
Assessment of variant pathogenicity across ancestries
Disentangling genetic ancestry vs social determinants of health in genomic research
Disease risk and outcome predictions
Portability of multimodal risk/outcome predictors across races, ancestries, and populations
Methods for development and/or adjustment of portable polygenic risk scores (PRS)
Incorporation of clinical factors avoiding embedded bias
Precision Oncology and Clinical Trials
Impact of race in cancer incidence and outcomes
Ancestry correlates somatic mutation landcapes
Ancestry impact on cancer subtyping and biomarkers
Measuring and increasing diversity in clinical trails
Resources for clinical research and medicine
Capture and curation of race/ethnicity data in health care
Development of diverse biobanks and EHR resources
Characterizing patients via genetics instead of race
Assessment of inequities across the precision medicine continuum
Ancestry correlates of drug responses and adverse events
Impact of racial differences on drug response on inequities
Methods to achieve "Pharmacoequity"
Fairness in artificial intelligence applied in medicine
Identifying and reducing racial biases in AI models
Paper Submission Deadline: August 1, 2023
Notification of Acceptance: September 11, 2023
Poster/Abstract Submission Deadline: December 4, 2023
Conference Date: January 3 - 7, 2024
The core of the conference consists of rigorously peer-reviewed full-length papers reporting on original work. All accepted papers will be published electronically and indexed in PubMed, and the best of these will be presented orally to the entire conference. PSB will also initiate submission to PubMed Central (PMC); however, PMC indexing applies only to papers that comply with the NIH Public Access Policy. Submitted papers are limited to twelve (12) pages (not including the cover letter) in the PSB publication format. Papers must be submitted to the PSB paper management system. For details see the Pacific Symposium of Biocomputing website.
Each paper must be accompanied by a cover letter. The cover letter should be the first page of your paper submission. The cover letter must state the following:
The email address of the corresponding author
Indicate that your submission is directed to the "Overcoming Health Disparities" session
The submitted paper contains original, unpublished results, and is not currently under consideration elsewhere
All co-authors concur with the contents of the paper
Please note that the submitted papers are reviewed and accepted on a competitive basis. At least three reviewers will be assigned to each submitted manuscript.
Researchers wishing to present their research without official publication are encouraged to submit a one page abstract by the abstract deadline listed above to present their work in the poster session.