PSB Session on Personalized Medicine Call For Papers
Call for Papers and Posters
data and discovery for improved health and therapy
Keynote Speaker: Jennifer Doudna
University of California, Berkeley and HHMI
January 4-8, 2016
Fairmont Orchid Resort, Kohala Coast
The Big Island of Hawaii
Rapid advances in sequencing, proteomics, biosensors, mobile health devices and apps
are opening up new vistas of personalized biomedical data. Meanwhile, clinical genome
editing, the ultimate personal genomics, is becoming tractable. To achieve the vaunted
goals of precision medicine and go from measurement to clinical translation, substantial
gains still need to be made in methods of data integration, analysis and interpretation.
We welcome all submissions relevant to this exciting and growing area of research.
We would like to invite contributions with relevance to improving
statistical and computational methodology in precision and personalized medicine
that describe either (1) a new problem including ideas on how to
tackle them, (2) a methodological improvement over solutions to existing
problems alongside empirical evaluation, (3) adaptations of existing
solutions to datasets with real-world scale. We encourage submissions
that span the full range from genotype to intermediate phenotype/physiology to
disease phenotype/physiology. The focus will be on methods applicable to large,
real-world problems. Both frequentist and Bayesian perspectives will
Examples of topics and problems within the scope of this session include :
- Novel statistical and computational approaches for genome
sequence analysis of omics data, such as DNA, RNA and bisulfite
Methodology for making use of rare and low frequency variants
arising from whole-genome and exome sequencing: combining
information across individuals or within a locus, prioritisation of
Gene expression studies: modeling hidden factors, characterizing
cell types in heterogeneous tissues, removing confounding effects,
inferring the activity of disease-relevant regulators.
- Methods of clinical phenotype prediction from genome sequence.
Models for longitudinal personal multi-omic data: high-dimensional
time series analysis, disease onset prediction, finding
genotype-dependent interactions between phenotypes and environment.
Predictive models for disease, including biomarker selection and
survival time prediction.
- Clinical applications of quantified self technology.
Development of causal models for genotype, gene expression,
disease labels and intermediate phenotypes.
Improvement of existing methods to address the increasing demand for
computational efficiency to allow for genome-scale applications.
Methods of analysis for high temporal resolution physiological/phenotypic data.
Comprehensive evaluation and comparison of existing methods in the
context of practical applications.
Innovative software for personalized medicine: for point-of-care use
by physicians, analysis software for consumers and clinical
geneticists, prioritisation and visualisation of genetic variation
and longitudinal phenotypes for personalised biomedical data.
topics within the subject area are welcome.
Please note that the submitted papers are reviewed and
accepted on a competitive basis.
- Paper submissions due:
July 27, 2015 August 13, 2015
- Notification of paper acceptance:
September 14, 2015
- Camera-ready final paper deadline:
October 5, 2015 at 23:59 PT
- Open for submissions for unreviewed poster abstracts: August 1, 2015
- Deadline for poster abstract submission: November 17, 2015 at noon PT
Please see the PSB paper format template and instructions at http://psb.stanford.edu/psb-online/psb-submit.
The file formats we accept are: postscript (*.ps) and Adobe
Acrobat (*.pdf)). Attached files should be
named with the last name of the first author (e.g. altman.ps or altman.pdf). Hardcopy submissions or unprocessed TeX or LaTeX files will be rejected without
Each paper must be accompanied by a cover letter. The cover letter must state
- The email address of the corresponding author.
- The specific PSB session that should review the
paper or abstract.
- The submitted paper contains original,
unpublished results, and is not currently under consideration elsewhere.
- All co-authors concur with the contents of the
Submitted papers are limited to twelve (12) pages
in our publication format. Please format your paper according to instructions
found at http://psb.stanford.edu/psb-online/psb-submit/.
If figures cannot be easily resized and placed precisely in the text, then it
should be clear that with appropriate modifications, the total manuscript
length would be within the page limit.
Please note that, unlike many biology conferences, the PSB proceedings is an archival,
peer-reviewed publication. PSB publications are indexed in MEDLINE/PubMed, and should be thought
of as short journal articles.
Poster presenters will be provided
with an easel and a poster board 32"W x 40"H (80x100cm). One poster from each paid
participant is permitted.