Announcement and Call for Papers

Computational Studies on the Design of Protease Inhibitors

C. Nick Hodge, chair

This track will emphasize the similarities and differences between proteases and their inhibitors, from a medicinal, biophysical, enzymological or theoretical perspective. However, bear in mind that the conference attracts a broad range of biological and computer scientists, so sufficient background information should be included in the posters and papers.

The minitrack includes poster sessions followed by a two-hour session in which posters are presented orally and questions of general interest are raised and addressed. I will also submit a few papers of broad interest and high quality to the main track for oral presentation after review.

Overview

The track will be a success if workers in the field of protease structure and inhibitor design leave the conference more familiar with methods used in other laboratories, and with a sense of how certain strategies may- or may not- have utility when they are applied to other classes of protease enzymes. Scientists from other disciplines should leave with more knowledge of how computational studies on protease inhibitor design is benefiting from and contributing to the general field of biocomputing, and where productive cross-disciplinary collaborations might be formed. Please see the description below for more details.

Content

Preference will be given to papers with the following content:

Data! For abstracts, reference to published work or work in progress is sufficient
General methodology if the utility is supported by experimental results
Computational predictions that are compared with experimental results from the same or other sources
Useful generalizations from studies on more than one protease enzyme or series of inhibitors

Novelty

All submittals are required to be original, unpublished research
Full papers will be published in the conference proceedings and should not be submitted elsewhere, prior to or after the conference
Posters can describe work in progress that can be published elsewhere

Review Process

All submittals will be peer reviewed
Posters need to have only the abstracts submitted and reviewed
Full papers (oral presentations) need to have the publication-ready text reviewed
Abstracts should be true abstracts, but detailed enough (with figures if possible) to allow review for quality, novelty and relevance

Submittals

Please submit via:

email in binhex version (preferably in Microsoft Word or some file that Word can open and retain formatting information)
by fax to (302) 695-2813
by snailmail on paper or disk to:

C. Nick Hodge

Head, Computer-Aided Drug Design
DuPont Merck Pharmaceutical Company
PO Box 80353
Wilmington, DE 19880-0353
If an electronic version is submitted, please use standard fonts.
Pages should be double spaced on hard copy
Deadline for submittal is July 27, 1995

General Notes

Feel free to be creative in presenting your material. If live demonstrations are desired I will try to arrange for a VCR and television or monitor.

For more information, please send email to hodgecn@lldmpc.dnet.dupont.com