Call for Papers and Posters

Molecular Bioinformatics for Diseases

Pacific Symposium on Biocomputing Session

January 5-9, 2009

Fairmont Orchid, Big Island

Hawaii, U.S.A.

This session focuses on computational analysis of the molecular mechanisms that underlie diseases. We are interested in studies that promote understanding of the molecular underpinnings of diseases and pathologies and in studies that could enhance diagnosis, analysis of prognosis and treatment. A main goal of this session is to bring together bioinformaticians, systems biologists, biomedical informaticians, physicians, pharmacologists, computer scientists, statisticians, members of the pharmaceutical industry and others to share their experience and scientific findings in this area. Of particular interest are studies that integrate biological, clinical, genomic and molecular data to provide disease-related predictions.

We would like to invite contributions that use informatics and computational approaches to analyze diseases at any scale of biology: from single nucleotide, through gene expression, RNA, protein, and protein interactions to the phenotypes of the organisms. Desired topics include, but are not limited to:

         macromolecular interactions in diseases

         miRNA and RNAi in diseases

         clinical, medical and pharmaceutical applications of micro-fluidics and other nanotechnologies

         biological networks, pathways and systems analysis of disease

         studies in cis/co- regulation in diseases

         association studies

         effects of SNPs and haplotypes on diseases

         protein, structure, misfolding or aggregation as related to diseases

         phenome-genome relationship and datasets

         comparative phenomics

         integrative phenomics or methods to integrate large datasets comprising heterogeneity of measurements and representation at the molecular level and phenotypic levels

         significant innovation in standards for exchanging and reusing phenomes or phenotypes associated with genetic or model organism databases or electronic medical records.

         original methodologies for quantitative trait loci or other genetic analyses that also include prior probabilities derived from high throughput phenomic studies

         visualization systems for cross-scale genome-phenome networks

Other topics within the subject area are welcome. Note that all submitted papers should make clear their relevance for the study of disease. If unsure whether your paper fits the session theme, please contact one of the co-chairs.

Session Co-Chairs
(alphabetical order)

Atul Butte

Stanford University

Maricel Kann

University of Maryland, Baltimore County

Yves Lussier

The University of Chicago

Yanay Ofran

Bar Ilan University

Predrag Radivojac

Indiana University



Submission Information


Please note that the submitted papers are reviewed and accepted on a competitive basis. At least three reviewers will be assigned to each submitted manuscript.


Important Dates

Paper submissions due: July 14, 2008

Notification of paper acceptance: September 8, 2008

Final paper deadline: September 22, 2008 at 11:59pm PT

Camera-ready tutorial handouts due: November 3, 2008




Paper Format

Papers must be submitted to the PSB 2009 paper management system at

Please click the "Not a user? Create an account with this site" link to create an author account and upload your paper.

All papers must be submitted in electronic format to the paper management system.

The file formats we accept are: postscript (*.ps) and Adobe Acrobat (*.pdf). Attached files should be named with the last name of the first author (e.g., altman.pdf). Hardcopy submissions or unprocessed TEX or LATEX files or electronic submissions not submitted through the paper management system will be rejected without review.

Each paper must be accompanied by a cover letter. The cover letter must state the following:

         The email address of the corresponding author

         The specific PSB session that should review the paper or abstract

         The submitted paper contains original, unpublished results, and is not currently under consideration elsewhere.

         All co-authors concur with the contents of the paper.


Submitted papers are limited to twelve (12) pages in our publication format. Please format and submit your paper according to instructions found at If figures cannot be easily resized and placed precisely in the text, then it should be clear that with appropriate modifications, the total manuscript length would be within the page limit.

Color pictures can be printed at the expense of the authors. The fee is $500 per page of color pictures, payable at the time of camera ready submission.

Contact Russ Altman (psb.hawaii @ for additional information about paper submission requirements.