Call for Papers and Posters

 

Protein Interactions and Disease

 
A Pacific Symposium on Biocomputing 2007 Session

January 3-7, 2007

Grand Wailea, Wailea, Maui

Hawaii, U.S.A.

 

 

There has been a tremendous progress in the study of protein interactions in recent years. The emergence of new experimental protocols and techniques, as well as the growth of sequence databases, allow scientists to capture more of the complexity of a biological process through computational techniques. One of the ultimate goals of biological sciences, and certainly the one with more impact to society, is to improve our understanding of the processes and events that lead to pathologies and diseases.

Some diseases are caused by simple genomic events that eliminate specific genes (e.g. frame shift mutations or insertion of viral genes). On the other end of the spectrum are “complex diseases”, such as heart or psychiatric diseases that are multifactorial and arguably could not be fully accounted for by simple molecular processes. Between these two ends lie many, if not most, of diseases which could be explained, at least in part, by combinations of subtle molecular events. Experimental studies indicate that in many diseases protein interactions play a key role. Hence, the analysis of protein interactions is crucial for the understanding of molecular basis of disease.

 

 

Session Topics

We would like to invite contributions addressing informatics approaches to understanding protein interactions involved in disease. In this context, submission topics can include, but are not limited to:

•  protein-protein interactions

•  protein-DNA/RNA interactions

•  analysis of protein networks and systems analysis of disease

•  studies on cis/co- regulation

•  genome-wide studies

•  effects of SNPs and haplotypes on protein interactions

•  studies on protein misfolding or aggregation as related to the emergence of diseases

•  protein interactions in drug discovery: drug design and target selection

 

Other topics within the subject area are welcome. Note that all submitted papers should make clear their relevance for the study of disease. If unsure whether your paper fits the session theme, please contact one of the co-chairs.

 

 

Last Year's Papers

All papers that were accepted to this session at PSB 2006 can be seen here.

 

Session Co-chairs

Maricel Kann, Ph.D.

National Center for Biotechnology Information, NIH

kann@ncbi.nlm.nih.gov


Yanay Ofran, Ph.D.

Columbia University

yanay.ofran@columbia.edu

Marco Punta, Ph.D.

Columbia University

punta@cubic.bioc.columbia.edu

Predrag Radivojac, Ph.D.

Indiana University

predrag@indiana.edu

 

 

Submission Information

 

Please note that the submitted papers are reviewed and accepted on a competitive basis. At least three reviewers will be assigned to each submitted manuscript.

 

Important Dates

•  Paper submission deadline: July 17, 2006

•  Notification of paper acceptance: September 6, 2006

•  Camera-ready copy deadline: September 25, 2006

•  Abstract deadline (for non-reviewed posters): November 10, 2006

 

All deadlines are at noon Pacific Standard Time.

 

Paper Format

All papers must be submitted to psb-submit @ helix.stanford.edu in electronic format. The file formats we accept are: postscript (*.ps) and Adobe Acrobat (*.pdf). Attached files should be named with the last name of the first author (e.g. altman.ps, altman.pdf, or altman.ps). Hardcopy submissions or unprocessed TEX or LATEX files will be rejected without review.


Each paper must be accompanied by a cover letter. The cover letter must state the following:

•  The email address of the corresponding author
•  The specific PSB session that should review the paper or abstract
•  The submitted paper contains original, unpublished results, and is not currently under consideration elsewhere.
•  All co-authors concur with the contents of the paper.

 
Submitted papers are limited to twelve (12) pages in our publication format. Please format your paper according to instructions found at http://psb.stanford.edu/psb-online/psb-submit/. If figures can not be easily resized and placed precisely in the text, then it should be clear that with appropriate modifications, the total manuscript length would be within the page limit.


Color pictures can be printed at the expense of the authors. The fee is $500 per page of color pictures, payable at the time of camera ready submission.


Contact Russ Altman (psb-submit @ helix.stanford.edu) for additional information about paper submission requirements.