Call for Papers and Posters

 

Computational Challenges in Comparative Genomics

 
A Pacific Symposium on Biocomputing 2010 Session

January 4-8, 2010

Fairmont Orchid, The Big Island of Hawaii

Hawaii, U.S.A.

 

 

Background

Comparative genomics has become a valuable tool in the study of cancer, of genetic diseases, of infertility, of pathogenicity and virulence of microbial parasites and of the evolution of species important to agriculture, agronomy, forestry and fishery. While pairwise comparisons of organisms and their genomes have long been a crucial tool in gene hunting and genome annotation, comparing several genomes at once only became possible in the last few years as sufficient numbers of genomes were released. The computational challenges are many and often very hard: almost every computational question about genomes is much more complex than analogous questions about DNA or protein sequences.

Research areas include construction of syntenic blocks from genome data; gene family evolution, including duplication and loss models, detection of horizontal transfer, and assignment of orthologs; identification of whole-genome duplication events; models and algorithms for genome rearrangements; reconstruction of ancestral genomes; detection of reticulation events; phylogenetic reconstruction from whole genomes; and uses of comparative genomic methods in evolution and systematics, in population genetics and genetic screening, in research into cancer, inherited disorders and human pathogens, and in agriculturally significant organisms. Such research includes model development, algorithm design, high-performance computing implementations, machine learning, data integration, analysis pipelines, and, of course, new insights into biology.

 

 

Session Theme

We invite contributions with a substantial and innovative computational component (such as computational models, algorithms, simulation studies, and computationally innovative analyses of biological data) in all areas of comparative genomics, including, but not limited to, gene family evolution, ancestral genome reconstruction, and integration with population genetics.


Note that all submissions must demonstrate the relevance to the session theme.
If unsure whether your paper fits the session theme, please contact Bernard Moret or one of the co-chairs.

 

 

Session Co-chairs

Bernard Moret, Ph.D., EPFL (Swiss Federal Institute of Technology), bernard.moret@epfl.ch

Webb Miller, Ph.D., Pennsylvania State University, wcm2@psu.edu

Pavel Pevzner, Ph.D., University of California at San Diego, ppevzner@cs.ucsd.edu

David Sankoff, Ph.D., University of Ottawa, sankoff@uottawa.ca


Submission Information

Please note that the submitted papers are reviewed and accepted on a competitive basis. At least three reviewers will be assigned to each submitted manuscript.

 

Important Dates

•  Paper submission deadline: July 13, 2009

•  Notification of paper acceptance: September 10, 2009

•  Camera-ready copy deadline: September 21, 2009

All deadlines are at midnight Pacific Standard Time.

 

Paper Format

Please see the PSB paper format template and instructions at http://psb.stanford.edu/psb-online/psb-submit.

The file formats we accept are: Postscript (*.ps) and Portable Document Format (*.pdf). Attached files should be named with the last name of the first author (e.g., altman.ps or altman.pdf). Hardcopy submissions or unprocessed TEX or LATEX files will be rejected without review.


Each paper must be accompanied by a cover letter. The cover letter must state the following:

•  The email address of the corresponding author
•  The specific PSB session that should review the paper or abstract
•  The submitted paper contains original, unpublished results, and is not currently under consideration elsewhere.
•  All co-authors concur with the contents of the paper.

 
Submitted papers are limited to twelve (12) pages in our publication format. Please format your paper according to instructions found at http://psb.stanford.edu/psb-online/psb-submit/. If figures cannot be easily resized and placed precisely in the text, then it should be clear that with appropriate modifications, the total manuscript length would be within the page limit.


Contact Russ Altman (psb.hawaii @ gmail.com) for additional information about paper submission requirements.